The closures started Friday night and will continue through Monday morning.
Berryville Mayor Tim McKinney says his city has already spent time and resources doing prep work.
The list includes a $50 million overlay program.
The southbound inside lane will be closed March 24-26 at about the 41 mile marker about one-half-mile north of the Hazel Street exit (Exit 42).
Downed power lines on Monday caused travel problems for eastbound traffic.
The closure is part of the preparation work to replace the bridge over the Arkansas River in Pulaski County. The Hwy. 10/Cantrell Rd. and La Harpe Blvd. access ramps will be removed.
The Arkansas State Highway Commission has approved a bid of more than $28 million for the project to be completed by a North Little Rock construction company.
Eastbound traffic now diverted to newly-built lanes.
Crews will improve the driving surface on the bridge located over Faulkner Lake Road.
Crews will repair potholes created by the recent winter weather. The work will be done between 65th Street and Roosevelt Road (mile markers 135 and 138).
They're so bad in Jacksonville along Highway 67/167 that they're causing traffic backups.
The city is tripling its road crews this week to combat the growing pothole problem.
It happened early Friday afternoon just east of 65th Street.
Construction crews to make extensive repairs to the bridge abutments and supports.
Crews will open the eastbound Shackleford Road overpass and the new temporary I-630 exit ramp to Baptist Health.
Crews will install a precast barrier wall and perform construction at the interchange through Feb. 14.
The work will require closing the southbound outside lane between 9 a.m. and 2 p.m. each day.
A crew will restripe the northbound and southbound lanes between I-30 and Highway 5 (Stagecoach Road).
Once it's opened, the intersection of Municipal Drive and Redmond Road will become a 3-way stop.